Bernard Gallez Selected Research

Neoplasms (Cancer)

1/2024	Sensitive simultaneous measurements of oxygenation and extracellular pH by EPR using a stable monophosphonated trityl radical and lithium phthalocyanine.
7/2023	Assessment of Hyperosmolar Blood-Brain Barrier Opening in Glioblastoma via Histology with Evans Blue and DCE-MRI.
3/2023	Mismatch between Bioluminescence Imaging (BLI) and MRI When Evaluating Glioblastoma Growth: Lessons from a Study Where BLI Suggested "Regression" while MRI Showed "Progression".
1/2023	Hyperpolarized 13C-Pyruvate to Assess Response to Anti-PD1 Immune Checkpoint Inhibition in YUMMER 1.7 Melanoma Xenografts.
1/2023	Metformin improves cancer immunotherapy by directly rescuing tumor-infiltrating CD8 T lymphocytes from hypoxia-induced immunosuppression.
12/2022	Targeting the bicarbonate transporter SLC4A4 overcomes immunosuppression and immunotherapy resistance in pancreatic cancer.
10/2022	Inhibition of Mitochondrial Redox Signaling with MitoQ Prevents Metastasis of Human Pancreatic Cancer in Mice.
10/2022	Statins Alleviate Tumor Hypoxia in Prostate Cancer Models by Decreasing Oxygen Consumption: An Opportunity for Radiosensitization?
9/2022	EPR Investigations to Study the Impact of Mito-Metformin on the Mitochondrial Function of Prostate Cancer Cells.
6/2022	Evaluation of Syrosingopine, an MCT Inhibitor, as Potential Modulator of Tumor Metabolism and Extracellular Acidification.

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Bernard Gallez Research Topics

Disease

123	Neoplasms (Cancer) 01/2024 - 06/2002
30	Hypoxia (Hypoxemia) 01/2023 - 01/2003
16	Melanoma (Melanoma, Malignant) 03/2024 - 03/2008
8	Breast Neoplasms (Breast Cancer) 01/2024 - 03/2015
7	Glioblastoma (Glioblastoma Multiforme) 07/2023 - 01/2018
7	Fibrosarcoma 05/2013 - 06/2002
5	Neoplasm Metastasis (Metastasis) 10/2022 - 07/2011
5	Ischemia 04/2019 - 08/2004
5	Wounds and Injuries (Trauma) 01/2018 - 11/2007
4	Rhabdomyosarcoma 01/2019 - 02/2015
4	Experimental Melanoma 05/2012 - 11/2007
3	Adenocarcinoma 12/2022 - 12/2008
3	Uterine Cervical Neoplasms (Cancer of the Cervix) 08/2021 - 02/2018
3	Glioma (Gliomas) 01/2019 - 07/2009
3	Hyperthyroidism 06/2011 - 10/2007
2	Nevus (Nevi) 03/2024 - 01/2022
2	Mitochondrial Diseases (Mitochondrial Disease) 10/2023 - 09/2021
2	Pancreatic Neoplasms (Pancreatic Cancer) 12/2022 - 10/2022
2	Prostatic Neoplasms (Prostate Cancer) 10/2022 - 09/2022
2	Squamous Cell Carcinoma (Epidermoid Carcinoma) 06/2022 - 12/2008
2	Obesity 12/2020 - 01/2020
2	Brain Neoplasms (Brain Tumor) 01/2020 - 02/2016
2	Necrosis 04/2016 - 03/2012
2	Skin Neoplasms (Skin Cancer) 06/2013 - 03/2012

Drug/Important Bio-Agent (IBA)

41	Oxygen (Dioxygen)IBA 03/2022 - 06/2002
20	carbogenIBA 01/2024 - 01/2003
11	Biomarkers (Surrogate Marker)IBA 01/2023 - 11/2006
10	Nitric Oxide (Nitrogen Monoxide)FDA Link 01/2013 - 06/2002
9	Melanins (Melanin)IBA 03/2024 - 03/2008
9	Lactic Acid (Lactate)FDA LinkGeneric 01/2023 - 12/2008
9	Glucose (Dextrose)FDA LinkGeneric 01/2023 - 12/2008
9	LipidsIBA 12/2020 - 03/2007
7	Paclitaxel (Taxol)FDA LinkGeneric 10/2019 - 01/2012
6	ferric oxide (iron oxide)IBA 06/2019 - 07/2009
5	Cyclophosphamide (Cytoxan)FDA LinkGeneric 01/2023 - 02/2006
5	Superoxides (Superoxide)IBA 10/2022 - 08/2014
4	Contrast MediaIBA 07/2023 - 11/2006
4	LuciferasesIBA 03/2023 - 07/2011
4	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 08/2015 - 11/2009
4	Proteins (Proteins, Gene)FDA Link 03/2014 - 03/2007
4	A-factor (Streptomyces)IBA 10/2012 - 06/2002
4	Insulin (Novolin)FDA Link 10/2006 - 06/2002
3	Free RadicalsIBA 03/2024 - 03/2008
3	Immune Checkpoint InhibitorsIBA 01/2023 - 01/2021
3	CytokinesIBA 01/2023 - 03/2014
3	AntioxidantsIBA 10/2022 - 10/2011
3	VemurafenibIBA 03/2022 - 03/2018
3	Pyruvic Acid (Pyruvate)IBA 03/2022 - 12/2016
3	DNA (Deoxyribonucleic Acid)IBA 01/2021 - 03/2007
3	Charcoal (Charbon)IBA 01/2021 - 04/2003
3	Hemoglobins (Hemoglobin)IBA 01/2020 - 09/2011
3	HydrogelsIBA 10/2019 - 06/2017
3	IntegrinsIBA 06/2019 - 11/2014
3	Radiation-Sensitizing AgentsIBA 01/2019 - 03/2003
3	GoldIBA 01/2019 - 09/2013
3	Choline (Choline Chloride)IBA 03/2018 - 05/2013
3	Fluorodeoxyglucose F18 (Fludeoxyglucose F 18)FDA Link 12/2016 - 12/2003
3	Sorafenib (BAY 43-9006)FDA Link 04/2016 - 10/2012
3	EnzymesIBA 01/2016 - 03/2010
3	Thyroxine (Levothyroxine)FDA LinkGeneric 06/2011 - 10/2007
3	NitritesIBA 04/2010 - 05/2008
3	Nitric Oxide Synthase (NO Synthase)IBA 07/2009 - 06/2002
3	Thalidomide (Thalomid)FDA Link 01/2008 - 01/2005
2	2-cyano-3-(1-phenylindol-3-yl)acrylateIBA 01/2024 - 08/2021
2	2- chloro- N- (4- chlorobiphenyl- 2- yl)nicotinamideIBA 10/2023 - 09/2021
2	Metformin (Glucophage)FDA LinkGeneric 01/2023 - 09/2022
2	pimonidazoleIBA 01/2023 - 09/2013
2	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2023 - 11/2010
2	Bicarbonates (Hydrogen Carbonate)IBA 12/2022 - 01/2017
2	mitoquinoneIBA 10/2022 - 03/2022
2	Glutathione (Reduced Glutathione)IBA 09/2022 - 02/2018
2	trametinibIBA 03/2022 - 03/2018
2	Mitogen-Activated Protein Kinase Kinases (MEKs)IBA 03/2022 - 03/2018
2	Monocarboxylic Acid TransportersIBA 08/2021 - 01/2012
2	Drug CombinationsIBA 10/2019 - 01/2016
2	Protons (Proton)IBA 01/2019 - 11/2014
2	Polylactic Acid-Polyglycolic Acid CopolymerIBA 09/2018 - 01/2018
2	AntibodiesIBA 01/2018 - 01/2016
2	lithium phthalocyanineIBA 01/2018 - 01/2015
2	fluoroazomycin arabinosideIBA 12/2017 - 10/2012
2	NitroimidazolesIBA 01/2017 - 10/2012
2	Pyruvate Dehydrogenase Acetyl-Transferring KinaseIBA 12/2016 - 11/2010
2	Small Interfering RNA (siRNA)IBA 04/2016 - 03/2010
2	fosbretabulin (combretastatin A4)IBA 02/2016 - 11/2014
2	FluorineIBA 01/2016 - 01/2008
2	EndoglinIBA 01/2016 - 09/2014
2	Gemcitabine FDA Link 01/2016 - 01/2008
2	MicellesIBA 02/2015 - 01/2012
2	EndocannabinoidsIBA 03/2012 - 01/2011
2	palmidrolIBA 03/2012 - 01/2011
2	CatalaseIBA 10/2011 - 08/2010
2	Prolyl Hydroxylases (Prolyl Hydroxylase)IBA 03/2010 - 02/2008
2	Hydrocortisone (Cortisol)FDA LinkGeneric 01/2010 - 01/2007

Therapy/Procedure

30	Therapeutics 01/2023 - 10/2006
30	Radiotherapy 01/2022 - 06/2002
13	Drug Therapy (Chemotherapy) 01/2022 - 01/2003
6	Aftercare (After-Treatment) 02/2015 - 06/2003
6	Lasers (Laser) 05/2013 - 06/2002
5	Immunotherapy 01/2023 - 01/2021
2	Injections 01/2020 - 09/2018